I am 35yrs old and I had suffer 2 mayor allergy events in my life. The first time I had an allergy crysis was 8 years ago, it itched like hell and the only way I was able to get rid of the hives (I had nettle rash in 90% of my body), was using steroids for 3 months and Zyrtec for the itching. Since then, I has been healthy, til 2 months ago that I have had another hive crysis due to a combination of factors. After using 5 dosis of strong steroids I was looking for a subsitute that helped me to control my reaction in bad days, after doing some research I read about DOA suplement enzyme and I understood what It does and I believed it can help me blocking the new formation of histamine in my body to stop inyecting me steroids til a found an alternative treatment or solution. Well, I have to say that It is effective. The instructions says that you need to take 2 capsules 20 minutes after each histamine rich food, but as this is the first time to me using enzime supplemets I started with only 1 capsule. It has decreased the reaction at least 60%, the effectiveness of this pill is amazing. But beware, is not safe to play with your inmune system without medical supervision. After a couple of days, when I noticed that the strengh of the reaction were minimal, I decided to stop taking DAO, and I only took it when any food gave me a strong reaction or when I felt that I will get worse. Then I took 1 capsule of DAO AFTER eating the food, and the result were almost in real time, in 5-10 minutes the reaction stopped and the hives started to dissapear. All the allergies and individuals are different, but as a person that has fail in despair to find a solution, I wanted to share my experience with this DAO supplement and the allergy that produces hives in the skin, this is the only thing besides benadryl that Is able to stop the hives in my skin, and that is something. But, as I though, this DAO supplement is not a treatment, it's a palliative, and I was tired of dealing with the crysis, even having a strict diet of low-histamine food. I understood that the mastocites of our body were over reacting for some reason, and that reason was outside the reach of the DAO supplement. So in the meantime, I found a new allergy specialyst that started treating me. He explains me the risk of taking DAO without studying/treat the main cause of the allergy. He started to treat my respiratory system, and he supressed me the DAO suplement. I have been without reaction til now, but I keep this DAO suplement as an emergency plan if I ever have a relapse, it is effective attacking the cause, not the consequence. Nevertheless from now on, this DAO supplement is a must-have in my emergency resources. Read more

Have struggled for years with histamine intolerance. After trying so many supplements this for me is the best to use when the meal has slightly higher levels of histamine than I would normally tolerate . Read more

Well done Amazon for supplying me with this product and at a good price! Read more

Works great for my daughter’s allergy’s. Easy to take. Has been helpful for sure Read more

Read the ingredients Read more

I'm mean, it's not really a surprise given the fillers. Why shellac? I'm probably the most sensitive person alive due to a long standing chronic illness that has gradually brought my body to a place where I'm overwhelmed with histamine on a daily basis. I can only eat three foods and have been looking for answers for years. I finally figured out on my own (because docs seem clueless) that I have histamine intolerance and the reactions I have to foods fall exactly in line with having an over abundance of it. You can imagine how excited I was to try this product! I might actually get my life back. Nope. I started the way I always do with new supplements and opened the capsule to try only one of those tiny little beads you find inside. Five minutes later I'm reacting quite noticeably having all of my hallmark indications of a histamine reaction. Queasiness, itchiness, swelling sensation in throat among the most noticeable. Good thing I didn't take a whole pill. Since I know I've never been allergic to pork and the bottle says you don't even absorb the DAO in the first place I figure it must be a reaction to one of the fillers. The only ones I feel like I'm new to are the shallac crospovidone and carboxymethylcellulose. Seriously people, you want to help the ones who most desperately need this product and you use all this extra crap? I contacted Seeking Health customer service before I tried this product after reading the negative reviews to try and get some answers as to what might be causing the bad reactions and, of course, they could give me nothing but the generic "everyone reacts differently". Don't bother trying to get any real answers or speculation out of them or even a direction to follow where to find answers. So anyways, obviously I decided to take a chance with bad results. I even tried to break open one of the tiny balls to see if it would reveal the contents are separate and encapsulated in hopes that I could painstakingly weed out the actual DAO itself but it looks like it's all melted together...just in case anyone is as desperate as me to find a way to make it work XD. Unfortunately, I can only wait for a product to come out without all of the dangerous fillers as I've already whittled my diet down to three foods so the anti histamine diet is out for me. Seeking Health, don't bother to request I contact your customer service for help. I've done that and you didn't have a whole lot to offer so please just leave me alone until (or IF) you decide to figure out a way to offer us desperate people DAO without all extras our bodies can't handle. Thanks guys. Have a great day. Have fun eating whatever you want and enjoying life while I eat my Teff bread for the millionth time in my life and waste away in my bed. EDIT: For anyone who's interested. I've learned that you can essentially make your own DAO by growing pea sprouts and consuming them fresh and raw approx. after 10 days of germination. It's not hard to find out how to do this yourself online. I'm resorting to this. Feel free to ask for an update on this if you're curious. Today is 9/25/19 and my first batch won't be ready for a couple of weeks. UPDATE: For anyone who cares... I tested out a small amount of pea sprout and had the same reaction to it as I did this supplement SO, the only thing I can conclude is that it has something to do with my body's reaction to DAO itself. I can't think of a reason for why something that's supposed to lower histamine actually has the opposite reaction in my body. Symptoms were noticeable in my ease of breathing, throat swelling, nausea, dizziness and face tingling/itching. I did read a study on how the Catalase enzyme is supposed to help break down the byproducts of when histamine is broken down but since my reaction was so quick after hitting my stomach with both the peas and this supplement I'm not sure it has anything to do with a low level of Catalase in my body or anything like that. If I learn anything new I'll post it! Read more

I got this because I have a non IGE mediated soy allergy and MCAS. I take it when I am at a restaurant and suspect I might have some soy. I definitely notice a difference as far as if I take this versus if I don’t. As far as histamine goes, fighting release helps a little bit with whatever you’ve got. What I notice most is a slightly less scratchy throat, better GI tolerance, and a *little* less bloat. I like it enough that I have bought quite a few bottles and believe it’s worth a try. Read more

Usually I buy this from the original website but I was in a hurry and I was impressed to find same quality product on Amazon, happy to know I can count on this if in need of it right away! Read more

وصل المنتج في سياره عير مكيفه السائق وضع الظرف عند مكيف السياره قبل التسليم فتحت الطرف عند السائق ولمست العلبه ساخنه جدا فتحت الثلاجه لم تكن تعمل لاكنها شكل فقط Read more

Received in April. I used other product first, decided to give it a try today but the item was already open despite having a seal on the outside. I am not sure if the product has been tampered with and I’m concerned about purchasing anything else from this brand again. Read more