I have been using this supplement for quite a while now. I use very large doses of B-12 every day for work, at the gym and as a scuba diver to maintain my energy levels and focus. This has been the best yet because of the strength of the capsules. My only "criticism" would be it's a little pricey. And I wish they offered it in a larger capacity. I go through 'em pretty quickly. But they are the best I've found yet. Read more

I never write reviews for supplements. I started taking this because I started using an NAD+ patch. They recommend taking a menthylation supplement. (I'd never even heard of it). I took 3 tablets in the morning before my patch. Within 30 or 45 minutes, I immediately felt great, energetic. I can't even explain it. I hadn't changed anything else. I thought , "no way". I decided to take it the next day as well. Same thing! More energy, clear head, sort of, maybe happier. I can't believe. I've never a supplement do that for me. I have taken everything. I am menopausal and take HT (Evamist and progesterone 200mg). But this is the first thing I have taken to truly have an immediate impact. I can't say you will have the same results. Like I mentioned, I bought for a completely different reason. I'm thrilled with how it makes me feel. It's been 4 days now. It's wonderful. Read more

I starting taking this after getting some (SpectraCell) testing done that said I was deficient in the various B vitamins and I had the MTHFR genetic defect that prevents methylation. I felt like crap for the last decade and my usual doctors weren't of any help. I eat very healthy and eat very well too as I thought that would make me better. I won't go into details but I always knew something was wrong and nothing else worked. Anyway, so i read about methyl folate and methylation, MTHFR etc. and I get this to start to "fix"it. Immediately I felt FAR worse than I ever did before. Headaches, brain fog, extreme fatigue. So I stopped taking it and I go back to the sites and learn this is normal reaction. So then I read you should boost your other B vitamins first without the methyl folate or b12 and then add this back in. So I did with a product called B Minus for about 2 months then I added this product back in. Now 2 months in to taking this I feel like I'm finally waking up and getting more energy and I feel fantastic. No side effects. And a lot of my old symptoms are gone or fading away. I held off writing a review b/c I've been so disappointed after taking so many supplements over the years but this one seems to be actually working. It can take 6 -12 months to see full results and get your levels back to where they should be so I can't imagine how I'll feel by then. I'm going to retest through Spectracell in 6 months and see where my levels are at. If you're not familiar with Spectracell, look into it. Most regular doctors won't have it and it's not covered under insurance. I actually went to a nutritionist to get it done. It's the best decision I've ever made for my health. I'm just sad that it took me so long to find the answers. Good luck to you. Read more

Only 5 days of taking it but I feel like it’s doing me good Read more

I am using this and have had no side effects or issues. Waiting for updated blood work to find how effective it is. I have used many Thorne products and have always enjoyed them. Read more